James J. O’Donnell Curriculum Vitae

Experience                                     

Rosalind Franklin University of Medicine and Science

            Associate Professor                                                                            9/22-present

            Assistant Professor                                                                               12/16-9/22

                           Department of Foundational Sciences and Humanities,

                                Discipline of Cellular and Molecular Pharmacology, Chicago Medical School

                           Department of Pharmaceutical Sciences, College of Pharmacy

                                                                                                       12/16-present

Pharmaconsultant, Inc.

            Vice President—Research and Development, Consultant in pharmacology and analytical toxicology

                                                                                                               8/15 – present

Indiana University School of Medicine—South Bend

            Postdoctoral Fellow                                                                                7/14-7/15

University of Chicago Department of Medicine

            Section of Pulmonary and Critical Care (Respiratory Biology Training Grant)

            Postdoctoral Fellow                                                                       5/14/12-5/13/14

Rush University Medical Center

            Department of Pharmacology

                           Research Associate                                                              1/1/12-4/12

University of Wisconsin-Madison

            Graduate Research Assistant in organometallic chemistry                           2003 – 2005

Northwestern University

            Research Assistant in organometallic/polymer chemistry                                    2002 – 2003    

Education

Rush University Medical Center

            Ph.D., Department of Pharmacology                                                         2006-2011

            Advisor:  Dr. Hazel Lum

            Project: “P120 Catenin Suppresses the Inflammatory Response in Endothelial Cells”        

University of Wisconsin-Madison

             Masters of Science, Chemistry                                                                2003-2005

Northwestern University

             Special Student in Chemistry            2001-2003

Massachusetts Institute of Technology (MIT)

            S.B. Electrical Engineering and Computer Science                                        1996-2001

 

 

Awards

American Society for Pharmacological and Experimental Therapeutics (ASPET)                          

            Division of Pharmacology Education Faculty Travel Award for Experimental Biology Conference 2018 Meeting

 

University of Chicago Department of Medicine Research Day

            Best Abstract, Translational Medicine/Fellow Category            2013        

 

Rush University

            Paul E. Carson, MD Award for Excellence in Pharmacology                                    2012

            Sigma Xi Poster Competition, 3rd out of 63 students at Rush University Research Forum             2010

 

Other

            National Merit Scholarship Winner                                                                    1996

 

Professional Organizations

American Academy of Clinical Toxicology (AACT)                                                 2015-present

American Society for Pharmacology and Experimental Therapeutics (ASPET)            2013-present

American Physiological Society (APS)                                                                    2008-2011

American College of Clinical Pharmacology (ACCP)                                               2015-present

 

Teaching Experience

Rosalind Franklin University (2013-present)

            Coordinator of Pharmacology Curriculum, Chicago Medical School (2019-present)

            Multisystems Block

                           Pharmacology of Shock                     2/20,2/21,3/22

                           Toxicology                                      2/20,2/21,2/22

                           Pharmacology: High Yield Drug Interactions        3/22

            Cardiovascular-Pulmonary-Renal (CPR) Block

                           Co-course Director (2022-present)

                           Antihypertensives                                           5/22

                           Antihypertensives Workshop                                              5/19,4/20,4/21,5/22

                           Chronic Kidney Disease Case Study Discussion (preceptor)      5/19,5/20,5/21,5/22

                           Acute Kidney Disease Case Study Discussion (preceptor)        5/19,5/20,5/21,5/22

                           Hyponatremia Case Study Discussion (preceptor)                  4/19,4/20,4/21,4/22

                           Cough and Fever Case Study Discussion (preceptor)              4/19,4/20,4/21,4/22

                           Dyspnea Case Study (preceptor)                                        4/19,4/20,4/21,4/22

                           Autonomic Nervous System (ANS) Problem Solving Workshop  3/19,3/20,3/21,3/22

                           Hypoxemia Case Study Case Study Discussion (preceptor)      3/19,3/20,3/21,4/22

                           Congestive Heart Failure Case Study Discussion (preceptor)    3/19,2/20,3/21,3/22

                           Heart Murmur Case Study Discussion (preceptor)                  3/19,3/20,3/21,3/22

                           Syncope Case Study Discussion (preceptor)                          3/19,3/20,3/21,3/22

                           Pharmacology of the Autonomic Nervous System                   2/19,3/20,3/21,3/22

                           Anti-hyperlipidemic Agents                                                 3/22                                       

           

            Gastrointestinal Block

                           Gastrointestinal Pharmacology III                                      2/19,2/20,2/21,2/22

                           Gastrointestinal Pharmacology IV and Liver Disease Pharmacology  2/19,2/20,2/21,2/22

                           Abdominal Pain Case Study Discussion (preceptor)            2/19,2/20,2/21,2/22

                           Jaundice and Liver Disease Case Study Discussion (preceptor)            2/19,2/20,2/21,2/22

                           Gastrointestinal Pharmacology I                                           1/19,1/20,1/21,1/22

                           Gastrointestinal Pharmacology II                                          1/19,1/20,1/21,1/22

                           GI Bleed Case Study Discussion (preceptor)                                  1/20,2/21,2/22

                           Lower GI Bleed Case Study Discussion (preceptor)                   1/19,1/20,1/21,1/22

                           Diarrhea Case Study Discussion (preceptor)                            1/19,1/20,1/21,1/22

                           Dysphagia Case Study Discussion (preceptor)                                            1/19     

            Infection-Immunology-Hematology Block

                           Sore Throat Case Study Discussion  (preceptor)             11/18,11/19,11/20,11/21

            Scientific Foundations of Medicine Block

                           Cancer Case Study                               12/21,10/22

                           Clinical Pharmacokinetics                               10/19

            Neurobehavioral Health

                           Movement Disorder Case Study Discussion (case writer, backup preceptor) 10/21,10/22

            Medical Pharmacology

                  Co-course director (2017-2019)

                           Autonomics Review                                         4/19

                           FDA Regulations & Drug Safety                         4/19

                           Toxicology                                                    4/19

                           Diabetes Small Group Discussion (co-lead facilitator)            3/19

                           Gastrointestinal Pharmacology                          2/19

                           Parkinson’s Disease Small Group Discussion (lead facilitator)             1/19

                           Psychopharmacology Small Group Discussion (co-facilitator)             12/18

                           Asthma Small Group Discussion (co-facilitator)   11/18

                           Cardiac Small Group Discussion (co-facilitator)   10/18

                           Hypertension Small Group Discussion (lead facilitator)            10/18

                           Anti-Hypertensives Problem Solving                 10/18

                           Integrated Autonomics Problem Solving            10/18

                           Autonomic Agents I-IV                                                     9/18

                           Psychopharm Small Group Discussion (co-facilitator)            12/18

                           Asthma Small Group Discussion (co-facilitator)   11/18

                           Cardiac Small Group Discussion (co-facilitator)   10/18

                           Hypertension Small Group Discussion (lead facilitator)            10/18

                           Anti-Hypertensives Problem Solving                 10/18

                           Integrated Autonomics (Problem Solving)          10/18

                           Autonomic Agents                                          9/18

                           Autonomics Review                                         5/18

                           FDA Regulation & Drug Safety                          4/18

                           Toxicology                                                    4/18

                           Diabetes – Group Discussion (co-facilitator)        3/18

                           Gastrointestinal (GI) Pharmacology                   2/18

                           Parkinson’s Disease – Group Discussion (co-facilitator)             1/18

                           Psychopharmacology – Group Discussion (co-facilitator)             12/17

                           Asthma  – Group Discussion (co-facilitator)       12/17

                           Cardiac  – Group Discussion (co-facilitator)       10/17

                           Anti-Hypertensives – Group Discussion (lead facilitator)             10/17

                           Autonomic Problem-solving                             10/17

                           Autonomic Agents                                          9/17

                           Autonomics Review                                                                     5/17

                           FDA Regulation & Drug Safety                          4/17

                           Toxicology                                                    4/17

                           Diabetes – small group discussion (facilitator)     3/17

                           Gastrointestinal Drugs                                     2/17

                           Parkinson’s Disease Treatment – Small Group Discussion                                1/17

                           Psychopharmacology – Small Group Discussion  12/16

           

            Pharmacology III (COP) 2020-present

                   Course Director (2020) (2 course directors in this course)

                           Toxicology I-III                               3/20,3/21,3/22

                           Drugs for Gout                                 3/20,3/21,3/22

                           Gastrointestinal Pharmacology I-II    2/20,3/21,2-3/22

                           Gastrointestinal Pharmacology III/Drugs for Liver Disease 3/20,3/21,3/22

                           Review Session                                5/20,5/21,5/22

                          

            Pharmacology II (COP) 2019-present

                   Course Director (2020)

                           Ethanol                                          2/20,2/21,2/22

                           Drugs of Abuse                                2/20,2/21,2/22

                           Opioid Analgesics and Antagonists       1/20,2/21,1/22

                           Drugs for Parkinsonism and Other Movement Disorders              12/19,1/21,1/22

                           Introduction to Pharmacology II                      11/19

           

            Pharmacology I (COP) 2019-present

                   Course Director (2019-present)

                           ANS Pharmacology Review                                                8/19,8/20,8/21,8/22

                        Introduction to Pharmacology 1;Diuretics for Cardiovascular Indications  8/19,8/20,8/21,8/22                                                                        

                           Antihypertensives I-III               8/19,8/20,8/21,8/22

                           Review Session (Diuretics, Antihypertensives, and Antihyperlipidemia Agents)                                                                                              8/19

                           Drugs for Angina/Cardiotonic Agents            9/19,9/20,9/21,9/22

                           Drugs for Hyperlipidemia                   9/20,9/21,8/22

                           Review Session (Drugs for Angina, Heart Failure, and Hyperlipidemia)      9/20,9/21,9/22

                           Anticoagulants                                 9/20,9/21,9/22

                           Antiarrhythmic Drugs I-III          9/19,9/20,9/21,9/22

                           Cardiovascular Problem-Solving Session            9/19,9/20,9/21,9/22

                           Review Session (Anticoagulants, Antiarrhythmics)            9/20,9/21

                           Diabetes Drugs I-III                     10/20,10/21,10/22

                           Dermatological Drugs                            10/20,10/21

                           Review Session (NMJ Blockers/Muscle Relaxants; Dermatological Drugs, Diabetes Drugs)                                        10/20

 

                  

                   Fundamentals of Pharmacology (COP) (2019-present)

                          Course Director (2019-present)

  Introduction to Course; Basic definitions, ADME Overview, Drug Absorption and    Distribution                         2/19,2/20,2/21,3/22

                                  Drug Elimination                                                              3/19,3/20,3/21,3/22

                                   Pharmacokinetics I                                                                3/20,3/21,3/22

                                  Pharmacokinetics II and Pharmacodynamics I                       3/19,3/20,3/21,3/22

                      Pharmacodynamics II; Drug Biotransformation/Pharmacogenomics; Review Session    3/19,3/20,3/21,3/22

                                  ANS Agents I                                                                   3/19,3/20,3/21,3/22

                                  ANS Agents II                                                                 4/19,4/20,4/21,4/22

                                  ANS Problem Solving                                                      4/19,4/20,4/21,3-4/22

                                  Drugs for Asthma                                                            4/19,4/20,4/21,4/22

                                  Diuretics                                                                         4/19,4/20,4/21,4/22

                                  Cardiovascular Pharmacology                                            4/19,4/20,4/21,5/22

                                  OTC Drugs for Self-Care                                                    5/19,5/20,5/21,5/22

                                  Pharmacology Review Session                                             5/19,5/20,5/21,5/22

 

            Forensic Toxicology and Pharmacology (COP) (2020-present)

                     Course Director (2020-present)

                           Introduction to Forensic Toxicology and Pharmacology; Overview of Forensic Concepts                                                                                                 11/20,11/21

                           Basic Pharmacokinetics Review                                            11/20,11/21

                           Alcohol                                                                            12/20,12/21

                           Opioids                                                                            12/20,12/21

                           Science of Drug Testing                                                      12/20,12/21

                           Cocaine                                                                           1/20,1/21

                           Forensic Case #1 – lorazepam                                             1/20,1/21

                           Marijuana                                                                        1/20,1/21

                           Forensic Case #2 – oxycodone                                             2/20,2/21

 

            Seminars in Cellular and Molecular Pharmacology

                           Course Director (2017-present)

 

            BBS Capstone Week (Board Review for Podiatry Students) (2018-present)

                           Autonomic Nervous System Pharmacology Review                                     2/21

                           Diabetes and Gastrointestinal Pharmacology Review                                   6/20                     Hormones and Gout Drugs Review                                                           6/20

                                   NSAIDS and Glucocorticoids Review                                                         6/20

                           Muscle Relaxants Review                                                                       6/20

                           Cardiovascular Pharmacology Review                                  6/18,6/19,6/20,3/21

                           Diabetes and Gastrointestinal Pharmacology Review              6/18,6/19,6/20,6/21                                                         Hormones and Gout Drugs Review                                                                                        6/18,6/19,6/20,6/21

                                   NSAIDS and Glucocorticoids Review                                    6/18,6/19,6/20,6/21

                           Muscle Relaxants Review                                                  6/18,6/19,6/20,6/21

                           Cancer Pharmacology Review                                                                 6/18

 

            Pharmacology (Pharmacy and Podiatry students 2017-6/2019; Podiatry students 2019-)                                                  

                           Gout Pharmacology                                  2/22,9/22

                           Gastrointestinal Pharmacology                          2/22

                           Drugs for Parkinsonism and Other Movement Disorders                               1/22

                           Gout Pharmacology                                         2/21

                           Gastrointestinal Pharmacology                          2/21

                           Drugs for Parkinsonism and Other Movement Disorders                               1/21

                           Autonomic Problem Solving                              7/20

                           Gout Pharmacology                                       10/20

                           Gastrointestinal Pharmacology                        10/20

                           Drugs for Parkinsonism and Other Movement Disorders              10/20

                           Gout Pharmacology                                         2/19

                           Gastrointestinal Pharmacology                          1/19

                           Drugs for Parkinsonism and Other Movement Disorders              1/19

                           Hypertension and Heart Disease Small Group Discussion (facilitator)             11/18

                           Drugs for Gout                                                                                          2/18

                           GI Drugs                                                                                              1/18

                           Diabetes Small Group Discussion (facilitator)                                              1/18

                           Drugs for Parkinsonism and Other Movement Disorders              1/18

                           Asthma Small Group Discussion (facilitator)       11/17

                           Hypertension and Heart Disease Small Group Discussion (facilitator)                                                              11/17

                           Drugs for Gout                                               2/17

           

           

            Neuropharmacology (Neuroscience graduate students) (2018, 2020)

                           Treatment for Parkinson’s Disease       1/18,1/20,1/22

           

            Advanced Molecular Pharmacology (GCMP 545)

                           Co-course director, research graduate students  8/17-12/17

                           Taught pharmacokinetics with emphasis on research applications

           

            Pharmaceutics II

                           Radiopharmaceuticals                                     1/19

                           Radiopharmaceuticals                                     1/18

            Pharmaceutics I

                           Colligative Properties                                      8/18

                           Colligative Properties                                      8/17

           

            General Pharmacology of the CNS                                     4/15

 

            Advanced Clinical Medicine                                              2015

            (Pharmacology component for physical therapy program)           

                           Analgesics and DMARDS                                 10/14

                           NSAIDs and Glucocorticoids                            10/14

                           Advanced Clinical Medicine and Pharmacology (HPTH 724),     2013

           

            Advanced Clinical Medicine and Pharmacology (HPTH 724)

                           Lecturer (5 lecture hours, physical therapy students)

                           NSAIDs and Glucocorticoids                             9/13

                           Analgesics                                                     9/13

                           Muscle Relaxants and Local Anesthesia             10/13

                           Medications for Traumatic Brain Injury (TBI) and Other Neurological  10/13

                           Conditions

                           Cardiovascular Pharmacology                         10/13

 

Rush University Medical Center (2008-2019)

            Cellular Pharmacology (GCC520-General Pharmacology)                                8/16,1/18,1/19

            Preparing a Scientific Manuscript (GCC508—Writing Practicum)                                     2016-18

       Mechanisms of Disease (2nd year Medical School)

                       Pharmacokinetics                                   2013-2015

            Medical Pharmacology (2nd year Medical School)                                       Pharmacokinetics                                                   2008-2015 

            Safety Pharmacology                                                                                    10/15

            Neurological Clinical Medicine and Pharmacology (HPTH644-15SP)                         2015

            Introduction to Medical Pharmacology with Medical Physiology,             2011

(course for all students in PhD, physician assistantship (P.A.), and biotechnology programs); taught Pharmacokinetics

            Advanced Pharmacokinetics            2010        

taught course to 2nd year Pharmacology graduate students

 

University of Wisconsin-Madison

            Teaching Assistant for General Chemistry                   2003-2005

Programs/Conferences attended

“At the Forefront of Hepatology”, University of Chicago Digestive Diseases Center, Chicago, IL. 5/18.

National Board of Medical Examiners (NBME) Invitational Conference for Educators, Philadelphia, PA. 5/18.

ASPET Annual Meeting. San Diego, CA. 4/18.

ASPET Annual Meeting. Chicago, IL. 4/17.

National Institute of Health (NIH) — PCR Methodology: Principles, Optimization and Applications (NIH Course) Bethesda, MD 7/14.

Marine Biological Laboratory—Strategies and Techniques for Analyzing Microbial Populations, Woods Hole, MA 8/15.

American College of Medical Toxicology Seminars in Forensic Toxicology: a Legal “Potpourri” (marijuana/alcohol) Denver, CO, 12/15.

MRO and Beyond: Advanced Drug Testing Interpretation (American College of Medical Toxicology Annual Scientific Meeting, Satellite Session) Huntington Beach, CA 3/16.

SEAK National Expert Witness Conference. Chicago, IL 5/16.                                                                           World Preclinical Congress. Boston, MA 6/16

Service

Vice President, American Society for Pharmacology and Experimental Therapeutics — Great Lakes Chapter (ASPET–GLC) (2021-present)

Secretary, American Society for Pharmacology and Experimental Therapeutics — Great Lakes Chapter (ASPET–GLC) (2017-21)

Judge for Oral Presentations and/or Poster Session, All School Research Forum, Rosalind Franklin University of Medicine and Science (2017-18)

Reviewer, Microvascular Research (2016-present)

Reviewer, American Journal of Therapeutics (2013-present)

Reviewer, PLoS One (2014)

Poster Session Judge, American Society for Pharmacology and Experimental Therapeutics-Great Lakes Chapter               (ASPET-GLC) Annual Meeting (2015)

Councilor, American Society for Pharmacology and Experimental Therapeutics, Great Lakes Chapter (ASPET-GLC) (2013-2015)

Activities Coordinator, Graduate Student Council (2006-2008)

               -coordinated silent auction and participated in other facets of running Emerald Ball fundraiser event (2007-2008)

 

publications – Journal Articles/Abstracts

  1. 8/2021, American Society for Pharmacology and Experimental Therapeutics (ASPET) Great Lakes Chapter Meeting, A Novel Pharmacokinetic Model of Ethanol Absorption for Forensic Use. Chicago, IL. Horner and O’Donnell III, J.J. (Abstract. Poster session. Presented by trainee, K. Horner)
  2. 8/2021, American Society for Pharmacology and Experimental Therapeutics (ASPET) Great Lakes Chapter Meeting, The Relationship Between Hydrophobicity and Fraction of Drug Metabolism. Chicago, IL. Zimulinda, D., Walters, D.E. , O’Donnell III, J.J. (Abstract.Poster session. Presented by trainee, D. Zimulinda)
  3. Zimulinda D and O’Donnell III, J.J., The Relationship Between Hydrophobicity and Fraction of Drug Metabolism. American Association of Pharmaceutical Scientists (AAPS) Pharmsci 360, (virtual) 10/2020. (Abstract).
  4. Mosnaim A.D., Wolf, M.E.; O’Donnell III, J.J.; Hudzik,(2019)β-Phenylethylamine and various monomethylated and para-halogenated analogs. Acute toxicity studies in mice, Drug and Chemical Toxicology, DOI: 10.1080/01480545.2018.1551899
  5. O’Donnell JT. O’Donnell JJ, Vogenberg FR. Forensic Analysis in Drug Litigation Finds Most Errors Occur with Commonly Used Therapies and Practices. P&T Journal. March 2019. 44(3).
  6. O’Donnell JT, O’Donnell JJ. Forensic Issues in OBGYN. Abstract of Proceedings. AJRI. September, 2017.
  7. Tian, Y.; Gawlak, G.; O’Donnell III, J.J.; Birukova, A.A.; Birukov, K.G.; Activation of Vascular Endothelial Growth Factor (VEGF) receptor-2 mediates endothelial permeability caused by cyclic stretch. J Biol Chem. 2016 May 6;291(19):10032-45. doi: 10.1074/jbc.M115.690487. Epub 2016 Feb 16.
  8. Gawlak, G.; Son, S.; Tian, Y.; O’Donnell III, J.J.; Birukov, K.; Birukova, A; Chronic high magnitude cyclic stretch stimulates EC inflammatory response via VEGF Receptor 2 dependent mechanism. Am J Physiol Lung Cell Mol Physiol.2016 Jun 1;310(11):L1062-70.
  9. Birukova, A.; Tian, Y.; Gawlak, G.; O’Donnell III, J.J.; Mambetsariev, I.; Modulation of endothelial inflammation by low and high magnitude cyclic stretch. PLoS One. 2016 Apr 29;11(4):e0153387.
  10. Tian, Y.; Tian, X.; Gawlak, G.; O’Donnell III, J.J.; Sacks, D.B.; and Birukova, A.B.; IQGAP1 regulates endothelial barrier function via EB1 – cortactin crosstalk. Mol Cell Biol. 2014 Sep 15;34(18):3546-58.
  11. O’Donnell III, J.J.; Birukova, A.A.; Beyer, E.C.; Birukov, K.G., 2014. Gap Junction Protein Connexin 43 (Cx43) Exacerbates Lung Vascular Permeability. PLoS One. 2014 Jun 26;9(6):e100931.
  12. Gawlak, G., Tian, Y.; O’Donnell III, J.J.; Tian, X.; Birukova, A.A.; and Birukov, K.G. Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin – p42/44MAPK – GEF-H1 complex. FASEB J. 2014 Jul; 28(7):3249-60.
  13. Cowan, C.; O’Donnell III, J.J.; Lum, H.; and Xu, S.; MicroRNA-146 Inhibits Thrombin-induced NF-κB Activation and Subsequent Inflammatory Responses in Human Retinal Endothelial Cells. 2014. Invest Ophthalmol Vis Sci. 2014 Jul 1;55(8):4944-51.
  14. O’Donnell JT, Marks D.H., Danese P., and O’Donnell III JJ, Marks DM. Drug Induced Liver Disease: Primer for the Primary Care Physician. DILD Vol 60, No 2 pages 49-104 Feb 2014 ISSN 0011-5029
  15. O’Donnell III JJ, O’Donnell JT and Juettner VM. 2012. Clinical Pharmacology for the Primary Care Physician. Disease-a-Month, October 2012.Elsevier.
  16. O’Donnell III, J.J.; Zhuge, Y.; Holian, O.; Cheng, F; Thomas L. L.; Forsyth C. B.; Lum, H.,   Loss of P120 Catenin Upregulates Transcription of Pro-inflammatory Adhesion Molecules in Human Endothelial Cells. Microvasc Res. 82(2), 105-12.
  17. Zhang, J.; O’Donnell III, J. J.; Holian, O.; Vincent, P.A.; Kim, K.S.; Lum, H., 2010. P120 Catenin Represses Transcription through Kaiso in Endothelial Cells. Res. 80(2), 233-9.
  18. O’Donnell, J. J.; Zhang, J.; Forsyth, C.; Lum, H., 2009. Intracellular movement of p120-catenin in Endothelial Cells and Implications for Transcriptional Regulation. FASEB J. 23, 1028.2, (abstract)
  19. Lum, H.; Cheng, F. O’Donnell, J. J.; Im, H.; and Holian, O., 2009. Adherens Junction Protein, P120 Catenin, Represses Transcriptional Activity of Endothelial Cells. FASEB J. 23:1028.3. (abstract)
  20. Jensen, T.R.; O’Donnell III, J. J.; Marks, T.J. 2004. Do/fn-Mediated Ring-Opening Ziegler Polymerization (ROZP) and Copolymerization with Mono- and Disubstituted Methylenecyclopropanes.  Diverse Mechanisms and a New Chain-Capping Termination Process.   23(4), 740-754.
  21. Seyam, A.M.; Stubbert, B.D.; Jensen, T.R.; O’Donnell III, J.J.; Stern, C.L.; Marks, T.J. 2004. Organolanthanide Constrained Geometry Complexes Modified for Catalysis: Synthesis, Structure, and Aminoalkane Hydroamination Properties of a Pyrrolidine-substituted Constrained Geometry Organolutetium Complex. Inorganica Chimica Acta, 357, 4029-4035.

 

publications – Books/Book Chapters

  1. O’Donnell III JJ. “Introduction to Endocrine Pharmacology”. In: Osborn S and Wecker L, eds. Brody’s Human Pharmacology, 7th Elsevier, Inc. In press.
  2. O’Donnell III JJ, Call GB, “The Pharmacology of Adrenocorticosteroid Disorders”, In: Osborn SI and Wecker L, eds. Brody’s Human Pharmacology, 7th Elsevier, Inc. In press.
  3. Call GB, O’Donnell III JJ “Treatment of Hypothalamic and Pituitary Disorders”, In: Osborn SI and Wecker L, eds. Brody’s Human Pharmacology, 7th Elsevier, Inc. In press.
  4. O’Donnell III JJ, Call GB, “Drug Therapy for the Management of Thyroid Disorders”, In: Osborn SI and Wecker L, eds. Brody’s Human Pharmacology, 7th Elsevier, Inc. In press.
  5. O’Donnell III JJ, Call GB, “Calcium Regulating Hormones and Other Agents Affecting Bone”, In: Osborn SI and Wecker L, eds. Brody’s Human Pharmacology, 7th Elsevier, Inc. In press.
  6. O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  7. O’Donnell III JJ., O’Donnell JT, Juettner V. “General Principles of Pharmacology” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  8. O’Donnell JT, O’Donnell III JJ. “Adverse Drug Reactions: Allergic focus” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  9. O’Donnell III JJ., O’Donnell JT “Drug Induced Falls”. In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  10. O’Donnell JT, O’Donnell III JJ., Marks DH, Danese P. “Drug Induced Liver Disease” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  11. Splawski JA, O’Donnell JT, O’Donnell III JJ. “Dangers of Opioids” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  12. Parran D, O’Donnell JT, O’Donnell III JJ. “Fetal Drug Exposure” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  13. O’Donnell JT, O’Donnell III JJ. “Medication Errors” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  14. O’Donnell JT, O’Donnell III JJ., Tedford SE. “Anticoagulants: Therapeutics, Risks, and Toxicities” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  15. O’Donnell JT, O’Donnell III JJ. “Pharmacist Malpractice and Liability” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  16. O’Donnell JT, O’Donnell III JJ. “Alcohol” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  17. Tedford SE, O’Donnell JT, O’Donnell III JJ, Bederka JP. “Marijuana: Pharmacology, Toxicology, and Forensic Issues” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  18. O’Donnell JT, O’Donnell III JJ, Vaughn W. “Involuntary Intoxication” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  19. O’Donnell III JJ, O’Donnell JT, ImobergSted A. “Forensic Drug Testing” In: O’Donnell III JJ, O’Donnell JT, Patel GP, Splawski JA, eds. O’Donnell’s Drug Injury, 5th Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: In press.
  20. O’Donnell III JJ, Somberg J, Idemyor V., O’Donnell JT, Eds. Drug Discovery and Development. Taylor & Francis Publishing. 2020.
  21. O’Donnell III JJ, Somberg J, O’Donnell JT, “Introduction to Drug Discovery and Development”. In: O’Donnell III JJ, Somberg J, Idemyor V., O’Donnell JT, eds.Drug Discovery and Development. Taylor & Francis Publishing. 2020.
  22. O’Donnell JJ, O’Donnell JT. Drug Induced Falls. In Bakken GM, LaRue C,

Cohen HH, Eds. Slips, Trips, Missteps and Their Consequences. Third Edition. L&J Publ., Tucson, 2020, In Press.

  1. O’Donnell J.T., O’Donnell III, J.J. Pharmacology of Ma In: Nesci J., St. Louis J.P. and Tiftickjian J.M. Medicolegal Aspects of Marijuana Arizona Edition. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2018.
  2. O’Donnell J.T., O’Donnell III, J.J. Marijuana: Pharmacology and Medical-Legal Issues. In: Callahan L.M. and Tiftickjian J.M. Medicolegal Aspects of Marijuana Washington Edition. Tuscon, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  3. O’Donnell, J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  4. O’Donnell III, J.J., O’Donnell J.T., and ImObersteg, A.D. Forensic Drug Testing. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  5. O’Donnell III, J.J., O’Donnell, J.T., Juettner V. General Principles of Pharmacology. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  6. O’Donnell, J.T., O’Donnell III, J.J. Allergic Drug Reactions. In: O’Donnell J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  7. O’Donnell, J.T., Marks, D.H., Danese, P., and O’Donnell III, J.J. Drug-induced Liver Disease. In: O’Donnell J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  8. O’Donnell, J.T., O’Donnell III, J.J. Dangers of Opiates. In: O’Donnell J.T., O’Donnell III, J.J. eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  9. O’Donnell III, J.J., O’Donnell, J.T. Drug-induced Falls. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  10. O’Donnell III, J.J., O’Donnell, J.T., ImObergsteg, A.D. Drug Testing in the Workplace. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  11. O’Donnell, J.T., O’Donnell III, J.J. Alcohol. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  12. O’Donnell, J.T., O’Donnell III, J.J., Benjamin, D.M. Marijuana: Pharmacology and Medical-Legal Issues. In: O’Donnell J.T., O’Donnell III, J.J., eds. O’Donnell’s Drug Injury. 4th ed. Tucson, AZ: Lawyers & Judges Publishing Company, Inc.: 2016.
  13. Benjamin D, O’Donnell JT and O’Donnell JJ. Pharmacology and Toxicology of Marijuana. In: Legal Medicine and Medical Ethics, 9th Edition, American College of Legal Medicine, 2015.
  14. O’Donnell JT and O’Donnell JJ. Pharmacology of Marijuana, in Tiftickjian J. Medical Legal Aspects of Marijuana – Colorado Edition. L&J Publishers, Tucson, 2015.
  15. O’Donnell JT and O’Donnell JJ. Alcohol in Civil Litigation. In: Caplan Y and Goldberger B eds., Garriott’s Medicolegal Aspects of Alcohol, 6th Edition, October 2014.
  16. O’Donnell III J.J., O’Donnell JT, and Juettner VM. 2012. In: Basic Pharmacology in Drug Injury: Liability, Analysis, and Prevention, 3rd L&J Publ, Tucson, AZ.

 

 

publications – videos

  1. O’Donnell III J.J. Understanding Opiate Toxicity; 7/2017. Available at:

http://pharmaconsultantinc.com/category/videos/

  1. O’Donnell III J.J. Autobrewery.; 11/2016. Available at: http://pharmaconsultantinc.com/category/videos/
  2. O’Donnell III J.J. Ambien Sleep Driving; 10/2016. Available at: http://pharmaconsultantinc.com/category/videos/
  3. O’Donnell III J.J. Retrograde Extrapolation; 8/2016. Available at: http://pharmaconsultantinc.com/category/videos/

 

Conferences/Departmental Seminars

  1. Lake Cook Dental Study Club, Cannabis and Dentistry. Glenview, IL. O’Donnell III JJ. 4/2022. (Invited Talk)
  2. 2021 National Association of Criminal Defense Lawyers (NACDL)/National College for DUI Defense (NCDD) DUI Defense Seminar, Changing the Variables in Retrograde Extrapolation. Las Vegas, NV. O’Donnell III JJ. 10/2021. (Invited Talk)
  3. 2021 National Association of Criminal Defense Lawyers (NACDL)/National College for DUI Defense (NCDD) DUI Defense Seminar, Challenging Drug Testing. Las Vegas, NV. O’Donnell III JJ. 10/2021. (Invited Talk)
  4. Chicago Medical School Faculty Retreat, Jigsaw Pedagogical Method Demonstration – Autonomic Nervous System Pharmacology. Zion, IL. O’Donnell III J.J. 5/2019.
  5. Chicago Medical School Faculty Retreat, Pecha Kucha Pedagogical Method Demonstration – Autonomic Nervous System Pharmacology, Zion, IL. O’Donnell III J.J. 5/19
  6. 11/2017. The Opioid Epidemic – Is Your Workplace Prepared?, conference sponsored by MRA-The Management Association and International Association of Employee Benefit Plans, Your Drug Testing Procedures–Time to Reevaluate. Waukesha, WI. O’Donnell III J.J. (Invited Talk)
  7. 9/2017. American Society for Reproductive Immunology (ASRI). Forensic Analysis of Adverse Drug Events and Litigation Claims in Ob/Gyn. Chicago, IL. O’Donnell J.T. and O’Donnell III J.J. (Invited Talk)
  8. 3/2016, Traffic Law CLE, Northwest Suburban Bar Association, DUI and Prescription Drugs, Arlington Heights, IL. (Invited Talk)
  9. 3/2016, Traffic Law CLE, Northwest Suburban Bar Association, Retrograde Extrapolation, Arlington Heights, IL. (Invited Talk)
  10. 4/2014, Indiana University School of Medicine Seminar, Gap Junction Protein Connexin 43 (Cx43) Exacerbates Lung Vascular Permeability; South Bend, IN. O’Donnell III, J.J. (Invited Talk)
  11. 2/2014, Haim and Jane Graumann Nagirner Weinstein Centennial Symposium Series, Rosalind Franklin University. Gap Junction Protein Connexin 43 (Cx43) Exacerbates Lung Vascular Permeability; Chicago, IL. O’Donnell III, J.J. (Invited Talk)
  12. 7/2013, International Gap Junction Conference, Gap Junction Protein Connexin 43 (Cx43) Exacerbates Lung Vascular Permeability. Charleston, SC. O’Donnell III, J.J.; Birukova, A.A.; Beyer, E.C.; Birukov, K.G. (Invited Talk)
  13. 6/2013, American Society for Pharmacology and Experimental Therapeutics (ASPET) Great Lakes Chapter Meeting, Gap Junction Protein Connexin 43 (Cx43) Exacerbates Lung Vascular Permeability. Chicago, IL.  O’Donnell III, J.J.; Birukova, A.A.; Beyer, E.C.; Birukov, K.G.
  14. 5/2013, American Thoracic Society Conference, Gap Junction Protein Connexin 43 (Cx43) Exacerbates Lung Vascular Permeability. Philadelphia, PA. O’Donnell III, J.J.; Birukova, A.A.; Beyer, E.C.; Birukov, K.G.
  15. 2/2013, Rush University Pharmacology Department Seminar, The Role of Connexins in the Regulation of Endothelial Permeability. Chicago, IL. O’Donnell III, J.J. (invited)
  16. 5/2011, Chicago Signal Transduction Symposium, Loss of P120ctn Upregulates Transcription of Pro-inflammatory Adhesion Molecules in Human Endothelial Cells. Chicago, IL. O’Donnell III, J.J.; Zhuge, Y.; Cheng, F.; Thomas, L.L.; Forsyth, C. B.; Lum, H.
  17. 5/2011, Rush University Research Forum. Loss of P120ctn Upregulates Transcription of Pro-inflammatory Adhesion Molecules in Human Endothelial Cells. Chicago, IL. O’Donnell III, J.J.; Zhuge, Y.; Cheng, F.; Thomas, L.L.; Forsyth, C. B.; Lum, H.
  18. 3/2011, Rush University Pharmacology Department Seminar, Loss of P120 Catenin Upregulates Transcription of Pro-inflammatory Adhesion Molecules in Human Endothelial Cells. Chicago, IL. O’Donnell, J.J.
  19. 4/2010, Rush University Research Forum, P120 Catenin Suppresses the Inflammatory Response in Endothelial Cells. Chicago, IL. O’Donnell, J.J.; Cheng, F.; Zhang, J.; Zhuge, Y.; Holian, O.; Lum, H.
  20. 4/2010, Experimental Biology Conference, P120 Catenin Suppresses the Inflammatory Response in Endothelial Cells. Anaheim, CA. O’Donnell, J.J.; Cheng, F.; Zhuge, Y.; Zhang, J.; Holian, O.; Lum, H.
  21. 2/2010, Rush University Pharmacology Department Seminar, P120 Catenin Suppresses the Inflammatory Response in Endothelial Cells. Chicago, IL. O’Donnell, J.J.
  22. 3/2009, Experimental Biology Conference, Nuclear Translocation of P120-catenin in Endothelial Cells and Implications for Transcriptional Regulation. New Orleans, LA, O’Donnell, J. J.; Zhang, J.; Forsyth, C.; Lum, H.
  23. 3/2009, Experimental Biology Conference, Adherens Junction Protein, P120 Catenin, Represses Transcriptional Activity of Endothelial Cells. New Orleans, LA. Lum, H.; Cheng, F.; O’Donnell, J. J.; Im, H.; Holian, O.
  24. 5/2009, Rush University Pharmacology Department Seminar, Intercellular Movement of P120-catenin in Endothelial Cells: Implications for Transcription Regulation. Chicago, IL. O’Donnell, J.J.
  25. 4/2009, Rush University Research Forum, Intracellular Movement of P120-catenin in Endothelial Cells and Implications for Transcriptional Regulation. Chicago, IL. O’Donnell, J.; Zhang, J.; Forsyth, C.; Lum, H.
  26. 4/2009, Rush University Research Forum, Adherens Junction Protein, P120 Catenin, Suppresses Transcription of Inflammatory Genes in Human Microvascular Endothelial Cells. Chicago, IL. Cheng, F.; O’Donnell III, J.J.; Im, H.J.; Holian, O.; Kim, K.S.; Lum, H.
  27. 5/2008, Rush University Pharmacology Department Seminar, Junctional Protein P120 Catenin Enhances Barrier Function and Represses Transcription in Endothelial Cells. Chicago, IL. O’Donnell, J.J.
  28. 4/2008, Rush University Research Forum, Junctional Protein P120 Catenin Enhances Barrier Function and Represses Transcription in Endothelial Cells. Chicago, IL. O’Donnell III, J. J.; Cheng, F.; Zhang, J.; Holian, O.; Predescu, S.; Lum, H.
  29. 5/2007, Rush University Pharmacology Department Seminar, Role of P120 Catenin in the Regulation of Kaiso-mediated Transcription Repression in Endothelial Cells, Chicago, IL. O’Donnell, J.J.
  30. 9/2006, Rush University Pharmacology Department Seminar, Role of P120 Catenin in the Regulation of Kaiso-mediated Transcription Repression in Endothelial Cells, Chicago, IL. O’Donnell, J.J.

 

 

Selected Laboratory techniques

Bioinformatics/Computer skills:

            QIIME, Uparse, UClust, Usearch, Oligotyping, UNIX, python, R, ADMET Predictor, Mathcad, Excel, SPSS, Reference Manager, Powerpoint, Microsoft Word

Analytical Chemistry: method validation for analytical instrumentation, nuclear magnetic resonance (nmr) spectroscopy, gas chromatography (GC), mass spectrometry (MS), high performance liquid chromatography (HPLC), Liquid chromatography/mass spectrometry (LC/MS), infrared spectrometry, thermal gravimetric analysis (TGA), differential scanning calorimetry (DSC), thin layer chromatography (TLC)

Synthetic Chemistry: air-free chemistry for organometallic synthesis (Schlenk line, glovebox), organic synthetic chemistry

Molecular biology:

molecular cloning and subcloning, DNA gel electrophoresis, RNAi technology, RT-PCR (with primer design,) RNA/DNA concentration measurement with Nanodrop

Protein work:

            SDS-PAGE, Western blot, protein concentration determination

Imaging techniques:

            immunofluorescence, immunohistochemistry, confocal microscopy, live imaging, Licor/Odyssey

Animal models:

intraperitoneal and subcutaneous injection, submandibular bleed, cardiac exsanguination, euthanasia, restraint.

Cell culture:

            transfection, endothelial cell types (HPAEC, PMVEC, HBMEC, BPAEC)

Specialized techniques:

Luciferase reporter assay, dye transfer assay (gap junction function), dye uptake assay (hemichannel function), neutrophil isolation and adhesion assay, electrical cell-substrate impedance signaling (ECIS) for monitoring barrier function, cyclic stretch, adenovirus infection, UV spectroscopy

 

Additional coursework

Design and Development of Educational Technology (MITx)                                                                       2017

Basic Computing for Bioinformatics (SP15-BIOS-60132-01) (audited, completed all exams and projects)             2015

Introduction to Computer Science and Programming Using Python (MITx – 6.00.1x)                                 2015

Introduction to Computational Thinking and Data Science (MITx – 6.00.2x)                                            2015